Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22497569 | 1.00 | ALDH1A1 (0.37) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL22497620 | 0.91 | MAPT (0.39) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL22497621 | 0.91 | MAPT (0.39) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL22284166 | 0.86 | POLB (0.39) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL20916968 | 0.86 | POLB (0.39) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL17567301 | 0.77 | POLB (0.39) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL20916815 | 0.76 | MAPT (0.41) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL20916814 | 0.76 | MAPT (0.41) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL30554306 | 0.76 | MAPT (0.41) | ALDH1A1MAPTPOLBGLARECQL | |
| SCHEMBL22284168 | 0.74 | L3MBTL1 (0.36) | MAPTPOLBGLARECQLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020200161-A1 | SALT OF INDAZOLYL-CONTAINING TRICYCLIC DERIVATIVE AND CRYSTAL FORM THEREOF | 上海翰森生物医药科技有限公司 | 2020-10-08 | — | — | WO | disclosed |