Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2198294 | 0.82 | LMNA (0.32) | BRD4BRD2LMNAGAASMN1; SMN2 | |
| SCHEMBL13873247 | 0.75 | — | — | |
| SCHEMBL435924 | 0.71 | BRD4 (0.33) | BRD4BRD2LMNAGAASMN1; SMN2 | |
| SCHEMBL27439659 | 0.68 | BRD4 (0.38) | BRD4BRD2ERN1 | |
| Hydrochloric Acid SCHEMBL27294572 | 0.68 | CYP1A2 (0.34) | BRD4BRD2LMNA | |
| SCHEMBL3417324 | 0.67 | GAA (0.37) | BRD4BRD2LMNAGAA | |
| SCHEMBL8394520 | 0.66 | MAPT (0.39) | BRD4BRD2LMNAGAA | |
| SCHEMBL18250371 | 0.63 | — | — | |
| SCHEMBL27925912 | 0.63 | ELANE (0.36) | BRD4GAA | |
| SCHEMBL6569258 | 0.62 | CACNA1F (0.48) | BRD4BRD2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020200284-A1 | PREPARATION METHOD FOR TRICYCLIC COMPOUND AND USE OF SAME IN FIELD OF MEDICINE | 上海华汇拓医药科技有限公司 | 2020-10-08 | — | — | WO | disclosed |