Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22497722 | 0.82 | BRD4 (0.33) | LMNAGAASMN1; SMN2ERN1BRD4 | |
| SCHEMBL30446556 | 0.74 | APOBEC3A (0.32) | GAASMN1; SMN2 | |
| SCHEMBL13873247 | 0.72 | — | — | |
| SCHEMBL2628978 | 0.70 | LMNA (0.32) | LMNAGAASMN1; SMN2BRD4BRD2 | |
| SCHEMBL435924 | 0.68 | BRD4 (0.33) | LMNAGAASMN1; SMN2BRD4BRD2 | |
| SCHEMBL20578250 | 0.67 | BRD4 (0.54) | ERN1BRD4BRD2 | |
| SCHEMBL15881127 | 0.67 | CACNA1F (0.37) | LMNAGAABRD4 | |
| SCHEMBL68794 | 0.65 | GAA (0.35) | LMNAGAASMN1; SMN2ERN1BRD4 | |
| Hydrochloric Acid SCHEMBL27294572 | 0.65 | CYP1A2 (0.34) | LMNABRD4BRD2 | |
| SCHEMBL27439659 | 0.65 | BRD4 (0.38) | ERN1BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777613-A | Preparation and application of pyrimidinedione indole and pyridone indole compounds | 中国药科大学 | 2020-10-16 | — | — | CN | claimed |
| CN-114984003-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-113544129-B | Tricyclic compound preparation method and application thereof in medicine field | 上海华汇拓医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-115054600-B | Aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-113929674-B | Compound containing 1, 4-dihydro quinazoline structure, preparation method and application thereof | 中国药科大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-112608320-B | Piperidine compound and preparation method and medical application thereof | 中国药科大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-110092782-B | Benzo-hexaazacyclo compound and preparation method and application thereof | 中国科学院广州生物医药与健康研究院 | 2022-10-21 | — | — | CN | disclosed |
| US-20220257774-A1 | AROMATIC AMINE AR AHD BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | HINOVA PHARMACEUTICALS INC. (CN) | 2022-08-18 | — | — | US | disclosed |
| US-20220177459-A1 | AROMATIC AMINE COMPOUND AND USE THEREOF IN PREPARATION OF AR AND BRD4 DUAL INHIBITORS AND REGULATORS | HINOVA PHARMACEUTICALS INC. (CN) | 2022-06-09 | — | — | US | disclosed |
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |
| US-7977334-B2 | N-(3-{2-[3-(6-amino-benzimidazol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide; beta(3)-Adrenoceptor agonists; antidiabetic, obesity modulator, insulin resistance | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20080234278-A1 | Beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | TRIESELMANN THOMAS | 2008-09-25 | — | — | US | disclosed |
| US-7132001-B2 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | disclosed |
| EP-1495015-B1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| US-20050245526-A1 | Beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-03 | — | — | US | disclosed |
| EP-1544200-A1 | 1,2,4 -TRIAZOLO 1,5-c PYRIMIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2005-06-22 | — | — | EP | disclosed |
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234278-A1 | Beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | ADRB1, ADRB3, ADRB2 | LMNA 966/4885GAA 1250/4885SMN1; SMN2 1888/4885 |
| US-20220257774-A1 | AROMATIC AMINE AR AHD BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | AR, BRD4, BRDT | LMNA 3557/4885GAA 3292/4885SMN1; SMN2 3282/4885 |
| US-20220177459-A1 | AROMATIC AMINE COMPOUND AND USE THEREOF IN PREPARATION OF AR AND BRD4 DUAL INHIBITORS AND REGULATORS | AR, BRD4, BICRA | LMNA 3386/4885GAA 4531/4885SMN1; SMN2 4092/4885 |
| US-20060058320-A1 | [1,2,4] Triazolo[1,5-c]pyrimidine derivatives | ADORA2A, ADORA1, ADORA3 | LMNA 4026/4885GAA 2621/4885SMN1; SMN2 3377/4885 |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | KRT18, JUP, IK | LMNA 1267/4885GAA 4524/4885SMN1; SMN2 4731/4885 |
| US-20050245526-A1 | Beta-agonists, methods for the preparation thereof and their use as pharmaceutical compositions | ADRB1, ADRB3, ADRB2 | LMNA 966/4885GAA 1250/4885SMN1; SMN2 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.