Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.37 |
| ▸ | LPL | P06858 | 11/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394481 | 0.80 | BACE1 (0.37) | LIPGLPLBACE1ROCK1CA1 | |
| SCHEMBL24571000 | 0.79 | DPP4 (0.33) | LIPGLPLBACE1ROCK1 | |
| SCHEMBL12501640 | 0.79 | LPL (0.38) | LIPGLPLROCK1CA1CA2 | |
| SCHEMBL12299346 | 0.79 | F11 (0.38) | LIPGLPLROCK1CA1CA2 | |
| SCHEMBL17418921 | 0.79 | F11 (0.38) | LIPGLPLROCK1CA1CA2 | |
| SCHEMBL14712054 | 0.77 | AKR1C3 (0.39) | LIPGBACE1ROCK1CA1CA2 | |
| SCHEMBL22547333 | 0.77 | PDPK1 (0.46) | LIPGLPLROCK1CA1CA2 | |
| SCHEMBL12501638 | 0.76 | F11 (0.38) | LIPGLPLROCK1CA1CA2 | |
| SCHEMBL12501513 | 0.76 | F11 (0.38) | LIPGLPLROCK1CA1CA2 | |
| SCHEMBL15912452 | 0.75 | LPL (0.37) | LIPGLPLROCK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020200284-A1 | PREPARATION METHOD FOR TRICYCLIC COMPOUND AND USE OF SAME IN FIELD OF MEDICINE | 上海华汇拓医药科技有限公司 | 2020-10-08 | — | — | WO | disclosed |