Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL267829 | 0.83 | CYP1A2 (0.53) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL31145677 | 0.83 | CYP1A2 (0.53) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL16961272 | 0.83 | GPR35 (0.42) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL7858061 | 0.80 | TDP1 (0.46) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL16797211 | 0.78 | TDP1 (0.47) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL29509474 | 0.78 | TDP1 (0.47) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL16119496 | 0.76 | CYP1A2 (0.47) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL28909321 | 0.76 | TDP1 (0.45) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL9004049 | 0.76 | TDP1 (0.48) | GPR35TSHRCYP1A2TDP1ALDH1A1 | |
| SCHEMBL16953155 | 0.74 | TDP1 (0.40) | GPR35TSHRCYP1A2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020202091-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-10-08 | — | — | WO | disclosed |
| WO-2020202091-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-10-08 | — | — | WO | disclosed |