SCHEMBL22499779

SCHEMBL22499779

CCCCCCC[C@@](C)(O)Cn1cc([N+](=O)[O-])nc1Cl

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 2/20 0.37
HSP90AA1 P07900 1/20 0.37
MITF O75030 1/20 0.37
SOS1 Q07889 1/20 0.35
PKM P14618 2/20 0.34
GSR P00390 1/20 0.33
TXNRD1 Q16881 1/20 0.33
POLB P06746 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29249828 1.00 ALDH1A1 (0.41) ALDH1A1KMT2AHSP90AA1MITFSOS1
SCHEMBL22499780 1.00 ALDH1A1 (0.41) ALDH1A1KMT2AHSP90AA1MITFSOS1
SCHEMBL5537615 0.82 ALDH1A1 (0.43) ALDH1A1KMT2AMITFSOS1PKM
SCHEMBL5537618 0.82 ALDH1A1 (0.43) ALDH1A1KMT2AMITFSOS1PKM
SCHEMBL5536388 0.82 ALDH1A1 (0.43) ALDH1A1KMT2AMITFSOS1PKM
SCHEMBL5537254 0.82 MITF (0.39) ALDH1A1KMT2AMITFSOS1PKM
SCHEMBL19518630 0.81 ALDH1A1 (0.38) ALDH1A1KMT2AMITFSOS1PKM
SCHEMBL19518629 0.81 ALDH1A1 (0.38) ALDH1A1KMT2AMITFSOS1PKM
SCHEMBL14562772 0.78 ALDH1A1 (0.44) ALDH1A1KMT2AMITFSOS1PKM
SCHEMBL5535208 0.78 MITF (0.40) ALDH1A1KMT2AMITFSOS1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874341-B Process for preparing derivatives of 1, 1-dialkylethane-1, 2-diols useful as intermediates 科学与工业研究委员会 2024-05-31 CN disclosed
WO-2020202205-A1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF 1,1-DIALKYLETHANE-1,2-DIOLS AS USEFUL INTERMEDIATES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2020-10-08 WO disclosed