Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 2/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398453 | 0.96 | AKR1C4 (0.64) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| SCHEMBL9487356 | 0.96 | AKR1C4 (0.64) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| Potassium Ion SCHEMBL9489269 | 0.96 | AKR1C4 (0.64) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| Lithium Ion SCHEMBL9019696 | 0.96 | AKR1C4 (0.64) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| Water SCHEMBL9399160 | 0.94 | AKR1C4 (0.62) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| SCHEMBL7182510 | 0.80 | AKR1C4 (0.72) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| SCHEMBL29387062 | 0.78 | AKR1C3 (1.00) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| SCHEMBL330545 | 0.78 | AKR1C3 (1.00) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| SCHEMBL895511 | 0.77 | AKR1C4 (0.67) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 | |
| SCHEMBL11800079 | 0.77 | AKR1C4 (0.67) | AKR1C4AKR1C3AKR1C2AKR1C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120003300-A1 | Composition Comprising Vascular Endothelial Growth Factor (VEGF) for the Treatment of Hair Loss | PANGAEA LABORATORIES LTD | 2012-01-05 | — | — | US | claimed |
| US-20090274677-A1 | ANTIOXIDANT FOR USE IN COSMETIC, MEDICATED AND PHARMACEUTICAL PREPARATIONS | MEDIK8 LIMITED (GB) | 2009-11-05 | — | — | US | claimed |
| EP-2113242-A1 | Antioxidant for use in cosmetic, medicated and pharmaceutical preparations | Pangaea Laboratories Limited (GB) | 2009-11-04 | — | — | EP | claimed |
| US-8221746-B2 | Antioxidant for use in cosmetic, medicated and pharmaceutical preparations | MEDIK8 LIMITED (GB) | 2012-07-17 | — | — | US | disclosed |
| US-20120116295-A1 | Topical Growth Factor Application Utilising a Microneedle Array | PANGAEA LABORATORIES LTD (GB) | 2012-05-10 | — | — | US | disclosed |
| US-20120003300-A1 | Composition Comprising Vascular Endothelial Growth Factor (VEGF) for the Treatment of Hair Loss | PANGAEA LABORATORIES LTD | 2012-01-05 | — | — | US | disclosed |
| US-20090274677-A1 | ANTIOXIDANT FOR USE IN COSMETIC, MEDICATED AND PHARMACEUTICAL PREPARATIONS | MEDIK8 LIMITED (GB) | 2009-11-05 | — | — | US | disclosed |
| EP-2113242-A1 | Antioxidant for use in cosmetic, medicated and pharmaceutical preparations | Pangaea Laboratories Limited (GB) | 2009-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274677-A1 | ANTIOXIDANT FOR USE IN COSMETIC, MEDICATED AND PHARMACEUTICAL PREPARATIONS | CAT, SOD3, GPX1 | AKR1C4 1915/4885AKR1C3 1870/4885AKR1C2 1418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.