SCHEMBL2250284

SCHEMBL2250284

Cc1ccc(S(=O)(=O)O)c(N=C2c3ccccc3-c3ccccc32)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MPL P40238 1/20 0.45
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ ELANE P08246 1/20 0.40
▸ ALDH1A1 P00352 6/20 0.38
▸ MAPT P10636 6/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ LMNA P02545 2/20 0.38
▸ NPSR1 Q6W5P4 2/20 0.38
▸ TP53 P04637 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ NR4A1 P22736 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18870477 0.76 MPL (0.44) MPLALDH1A1MAPTKMT2AMEN1
SCHEMBL1808666 0.76 MPL (0.44) MPLALDH1A1MAPTKMT2AMEN1
SCHEMBL8820520 0.73 PTGDR2 (0.47) MPLCA2ELANEALDH1A1MAPT
SCHEMBL3885120 0.72 ELANE (0.47) MPLCA1CA2ELANEALDH1A1
SCHEMBL7857421 0.71 ELANE (0.46) MPLELANEALDH1A1MAPTKMT2A
SCHEMBL3151094 0.70 HDAC7 (0.49) MPLCA2ELANEALDH1A1MAPT
SCHEMBL25266704 0.70 ELANE (0.49) MPLELANEALDH1A1MAPTKMT2A
SCHEMBL5597375 0.70 MAOB (0.44) MPLCA1CA2ELANEALDH1A1
SCHEMBL9131035 0.70 ELANE (0.44) MPLELANEALDH1A1MAPTKMT2A
SCHEMBL2516098 0.70 ELANE (0.44) MPLELANEALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1626309-B1 Hologram recording material, hologram recording method and holographic optical element FUJIFILM CORP (JP) 2011-07-27 — — EP disclosed
EP-1626309-A2 Hologram recording material, hologram recording method and holographic optical element Fuji Photo Film Co., Ltd. (JP) 2006-02-15 — — EP disclosed
US-20050214650-A1 Hologram recording material, hologram recording method, optical recording medium, three-dimensional display hologram and holographic optical element FUJI PHOTO FILM CO., LTD. 2005-09-29 — — US disclosed
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