Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12836133 | 0.78 | ALDH1A1 (0.47) | CNR2ALDH1A1SMN1; SMN2KDM4EGFER | |
| SCHEMBL5358916 | 0.78 | CNR2 (0.45) | CNR2ALDH1A1SMN1; SMN2KDM4EGFER | |
| SCHEMBL12836132 | 0.77 | MAPT (0.48) | CNR2ALDH1A1SMN1; SMN2KDM4EGFER | |
| SCHEMBL10694482 | 0.72 | ALDH1A1 (0.48) | CNR2ALDH1A1SMN1; SMN2KDM4EGFER | |
| SCHEMBL2440672 | 0.69 | NPC1 (0.54) | CNR2ALDH1A1SMN1; SMN2KDM4EGFER | |
| Acrylamide SCHEMBL28867195 | 0.68 | NPC1 (0.53) | ALDH1A1SMN1; SMN2KDM4EGFERGAA | |
| SCHEMBL29639814 | 0.67 | ITGB3 (0.54) | CNR2ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL4873981 | 0.67 | NPC1 (0.61) | ALDH1A1SMN1; SMN2KDM4EGFERGAA | |
| SCHEMBL4767629 | 0.67 | NPC1 (0.61) | ALDH1A1SMN1; SMN2KDM4EGFERGAA | |
| SCHEMBL1397421 | 0.67 | NPC1 (0.61) | ALDH1A1SMN1; SMN2KDM4EGFERGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793515-B2 | Compounds advantageous in the treatment of central nervous system diseases and disorders | AURIMMED PHARMA, INC. (US) | 2020-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793515-B2 | Compounds advantageous in the treatment of central nervous system diseases and disorders | SMN1; SMN2, HDAC6, CTSA | CNR2 56/4885ALDH1A1 1386/4885SMN1; SMN2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.