Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12745595 | 0.87 | ACHE (0.56) | ACHECES1HDAC6HDAC1HDAC8 | |
| SCHEMBL8755253 | 0.87 | CES1 (0.70) | ACHECES1HDAC6HDAC1CES2 | |
| SCHEMBL30166168 | 0.81 | CES1 (0.65) | ACHECES1HDAC6HDAC1CES2 | |
| SCHEMBL1273634 | 0.81 | CES1 (0.65) | ACHECES1HDAC6HDAC1CES2 | |
| SCHEMBL6263144 | 0.79 | ACHE (0.59) | ACHECES1HDAC6 | |
| SCHEMBL6295066 | 0.79 | CES1 (0.65) | ACHECES1KMOHDAC6HDAC1 | |
| SCHEMBL7052467 | 0.78 | ACHE (0.58) | ACHECES1HDAC6HDAC1CES2 | |
| SCHEMBL7048349 | 0.78 | ACHE (0.58) | ACHECES1HDAC6 | |
| SCHEMBL7048345 | 0.78 | ACHE (0.58) | ACHECES1HDAC6HDAC1CES2 | |
| SCHEMBL19267581 | 0.78 | ACHE (0.68) | ACHECES1HDAC6HDAC1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | THE SCRIPPS RESEARCH INSTITUTE | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | ALDH1A2, DDT, CLTB | ACHE 914/4885CES1 2814/4885KMO 2303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.