Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592004 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL25511794 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL21541121 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL18437016 | 0.79 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL26034544 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNA | |
| SCHEMBL26716980 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL26757008 | 0.75 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL19367996 | 0.75 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL26696658 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL26049492 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020205564-A1 | CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES | IMMUNOGEN, INC. (US) | 2020-10-08 | — | — | WO | disclosed |