Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518525 | 0.78 | MAPK1 (0.50) | ALDH1A1HSD17B10RECQLMAPTCA1 | |
| SCHEMBL514043 | 0.77 | HSD17B10 (0.54) | ALDH1A1HSD17B10RECQLMAPTCA1 | |
| SCHEMBL13359585 | 0.77 | HSD17B10 (0.54) | ALDH1A1HSD17B10RECQLMAPTCA1 | |
| SCHEMBL1576857 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10RECQLCA1CA2 | |
| SCHEMBL2303355 | 0.76 | MAPT (0.48) | ALDH1A1HSD17B10RECQLMAPTCA1 | |
| SCHEMBL19381979 | 0.74 | MAPK1 (0.46) | ALDH1A1HSD17B10RECQLMAPTCA1 | |
| SCHEMBL2889414 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HSD17B10RECQLCA1CA2 | |
| SCHEMBL31518578 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HSD17B10RECQLMAPTCA1 | |
| SCHEMBL22567 | 0.72 | ALDH1A1 (0.72) | ALDH1A1HSD17B10RECQLCA1CA2 | |
| SCHEMBL27909482 | 0.72 | ALDH1A1 (0.72) | ALDH1A1HSD17B10RECQLCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |
| EP-3539951-B1 | NOVEL PYRIMIDINE COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER AND INFLAMMATORY DISEASES | KOREA RES INST CHEMICAL TECH (KR) | 2020-10-07 | — | — | EP | disclosed |
| CN-1867553-B | Sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents | SCHERING AG | 2011-06-08 | — | — | CN | disclosed |
| CN-1867553-A | Sulfoximine-substituted pyrimidines as CDK-and/or VEGF inhibitors, their production and use as pharmaceutical agents | SCHERING AG (DE) | 2006-11-22 | — | — | CN | disclosed |