Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576857 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL20248084 | 0.77 | CYP19A1 (0.52) | ALDH1A1HSD17B10LMNACES1RECQL | |
| SCHEMBL31518578 | 0.77 | ALDH1A1 (0.54) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL13359585 | 0.77 | HSD17B10 (0.54) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL10507359 | 0.77 | CYP1A2 (0.58) | ALDH1A1HSD17B10ACHELMNATDP1 | |
| SCHEMBL514043 | 0.77 | HSD17B10 (0.54) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL27909482 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL22567 | 0.77 | ALDH1A1 (0.72) | ALDH1A1HSD17B10ACHELMNACES1 | |
| SCHEMBL9022447 | 0.77 | — | — | |
| SCHEMBL8779823 | 0.77 | LOXL2 (0.44) | ALDH1A1HSD17B10ACHELMNACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1418111-A | Novel Ligands and method for preparing same | NAT UNIV SINGAPORE (SG) | 2003-05-14 | — | — | CN | claimed |
| EP-3718545-A1 | ANTITUMOR AGENT | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| WO-2017162390-A1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2017-09-28 | — | — | WO | disclosed |
| EP-2268747-B1 | MODIFIED PIGMENTS HAVING REDUCED PHOSPHATE RELEASE, AND DISPERSIONS AND INKJET INK COMPOSITIONS THEREFROM | CABOT CORP (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2760838-B1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2017-05-10 | — | — | EP | disclosed |
| CN-102596204-B | New nucleic acid prodrugs and using method thereof | 波涛生命科学有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20150352108-A1 | AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBK1 AND/OR IKK EPSILON | ALZHEIMER'S INSTITUTE OF AMERICA (US) | 2015-12-10 | — | — | US | disclosed |
| US-20150274770-A1 | NOVEL PROCESS AND INTERMEDIATE FOR PREPARATION OF ULIPRISTAL | LUPIN LIMITED (IN) | 2015-10-01 | — | — | US | disclosed |
| WO-2014060888-A1 | NOVEL PROCESS AND INTERMEDIATE FOR PREPARATION OF ULIPRISTAL | LUPIN LIMITED (IN) | 2014-04-24 | — | — | WO | disclosed |
| US-20120238540-A1 | AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF IKK EPSILON AND/OR TBK1 | MYREXIS, INC. (US) | 2012-09-20 | — | — | US | disclosed |
| CN-102596204-A | Novel nucleic acid prodrugs and methods use thereof | ONTORII INC | 2012-07-18 | — | — | CN | disclosed |
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-7674807-B2 | Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides | BAYER CROPSCIENCE AG (DE) | 2010-03-09 | — | — | US | disclosed |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |
| CN-1418111-A | Novel Ligands and method for preparing same | NAT UNIV SINGAPORE (SG) | 2003-05-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274770-A1 | NOVEL PROCESS AND INTERMEDIATE FOR PREPARATION OF ULIPRISTAL | ADH1A, UGT2B17, ADH5 | ALDH1A1 14/4885HSD17B10 329/4885ACHE 2160/4885 |
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | DDT, SQOR, CYP2S1 | ALDH1A1 1137/4885HSD17B10 2256/4885ACHE 59/4885 |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | CHRM1, KCNH1, DDT | ALDH1A1 2697/4885HSD17B10 4256/4885ACHE 11/4885 |
| US-20150352108-A1 | AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF TBK1 AND/OR IKK EPSILON | TBK1, NFKBIA, CHUK | ALDH1A1 4754/4885HSD17B10 4821/4885ACHE 3108/4885 |
| US-20120238540-A1 | AMINO-PYRIMIDINE COMPOUNDS AS INHIBITORS OF IKK EPSILON AND/OR TBK1 | TBK1, NFKBIA, IKBKB | ALDH1A1 4626/4885HSD17B10 4668/4885ACHE 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.