Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.33 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20808702 | 0.82 | PARP1 (0.38) | MAPK1MAOAHSD17B10ABHD6 | |
| SCHEMBL15796712 | 0.79 | HSD17B3 (0.38) | HSD17B10ABHD6 | |
| SCHEMBL21593485 | 0.78 | ABHD6 (0.36) | MAOAABHD6 | |
| SCHEMBL30130896 | 0.78 | ABHD6 (0.36) | MAOAABHD6 | |
| SCHEMBL20985793 | 0.75 | EGFR (0.37) | MAPK1ITGB3ITGA2BITGA2ABHD6 | |
| SCHEMBL22532176 | 0.74 | ACHE (0.38) | MAPK1ACHEITGB3ITGA2BITGA2 | |
| SCHEMBL289293 | 0.73 | BRD4 (0.41) | HSD17B10ABHD6 | |
| SCHEMBL22749555 | 0.73 | ACHE (0.37) | MAPK1ACHEITGB3ITGA2BITGA2 | |
| SCHEMBL1685821 | 0.73 | ACHE (0.39) | MAPK1ACHEITGB3ITGA2BITGA2 | |
| SCHEMBL14876149 | 0.70 | ABHD6 (0.35) | MAOAHSD17B10ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3952870-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | Nanjing Zhengxiang Pharmaceuticals Co., Ltd. (CN) | 2022-02-16 | — | — | EP | disclosed |
| WO-2020210379-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | HANGZHOU ZHENGXIANG PHARMACEUTICALS CO., LTD. (CN) | 2020-10-15 | — | — | WO | disclosed |