SCHEMBL225342

SCHEMBL225342

CCCc1ccc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4860917 0.87 KDM4E (0.36)
SCHEMBL3870601 0.86 KDM4E (0.42)
SCHEMBL1487718 0.86 DPP4 (0.36)
SCHEMBL1414863 0.85 KDM4E (0.45)
SCHEMBL3357183 0.85 TDP1 (0.41)
SCHEMBL3883593 0.83 KDM4E (0.40)
SCHEMBL3076471 0.83 KDM4E (0.40)
SCHEMBL15791269 0.83 KDM4E (0.40)
SCHEMBL3877421 0.83 KDM4E (0.40)
SCHEMBL1756488 0.83 KDM4E (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221737-A Synthesis method of bis (5-propyl-2-thienyl) phosphorus chloride 浙江九洲药业股份有限公司 2024-06-21 CN claimed
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN claimed
CN-112920813-A Photo-thermal responsive chiral photosensitive liquid crystal dopant containing azobenzene binaphthalene 湘潭大学 2021-06-08 CN claimed
CN-118221737-A Synthesis method of bis (5-propyl-2-thienyl) phosphorus chloride 浙江九洲药业股份有限公司 2024-06-21 CN disclosed
CN-118221737-A Synthesis method of bis (5-propyl-2-thienyl) phosphorus chloride 浙江九洲药业股份有限公司 2024-06-21 CN disclosed
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN disclosed
EP-3495349-B1 (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS ORYZON GENOMICS SA (ES) 2023-06-28 EP disclosed
CN-107011920-B Liquid-crystalline medium comprising thiophene derivatives 默克专利股份有限公司 2021-06-22 CN disclosed
CN-112920813-A Photo-thermal responsive chiral photosensitive liquid crystal dopant containing azobenzene binaphthalene 湘潭大学 2021-06-08 CN disclosed
WO-2021074898-A1 MALIC ENZYME INHIBITORS SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2021-04-22 WO disclosed
CN-110372662-A Liquid-crystal compounds and its synthetic method based on pentamethylene bithiophene skeleton 西安近代化学研究所 2019-10-25 CN disclosed
US-20100227859-A1 TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS WYETH LLC 2010-09-09 US disclosed
US-20100130468-A1 INDOLE CARBOXAMIDES AS IKK2 INHIBITORS GLAXOSMITHKLINE LLC 2010-05-27 US disclosed
EP-2144893-A2 TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS Wyeth a Corporation of the State of Delaware (US) 2010-01-20 EP disclosed
US-20090324577-A1 6-11 Bicyclic Ketolide Derivatives OR YAT SUN 2009-12-31 US disclosed
WO-2008137816-A2 TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS WYETH (US) 2008-11-13 WO disclosed
US-7405003-B2 Organic semiconductor material, organic semiconductor structure, and organic semiconductor device DAI NIPPON PRINTING CO., LTD. (JP) 2008-07-29 US disclosed
US-7405003-B2 Organic semiconductor material, organic semiconductor structure, and organic semiconductor device DAI NIPPON PRINTING CO., LTD. (JP) 2008-07-29 US disclosed
US-7405003-B2 Organic semiconductor material, organic semiconductor structure, and organic semiconductor device DAI NIPPON PRINTING CO., LTD. (JP) 2008-07-29 US disclosed
US-20060076554-A1 Organic semiconductor material, organic semiconductor structure, and organic semiconductor device DAI NIPPON PRINTING CO., LTD. (JP) 2006-04-13 US disclosed