SCHEMBL3870601

SCHEMBL3870601

CCCCc1ccc(Br)s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 4/20 0.41
MAPT P10636 4/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
BRCA1 P38398 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3357183 0.94 TDP1 (0.41) KDM4ETDP1ALDH1A1MAPTMEN1
SCHEMBL1304794 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL3877421 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL3076471 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL3883593 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL20122066 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL15791269 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL1756488 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL27842939 0.92 KDM4E (0.40) KDM4ETDP1ALDH1A1HSD17B10POLB
SCHEMBL225342 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN claimed
CN-112920813-A Photo-thermal responsive chiral photosensitive liquid crystal dopant containing azobenzene binaphthalene 湘潭大学 2021-06-08 CN claimed
CN-112920813-B Photo-thermal response chiral photosensitive liquid crystal dopant containing azobenzene binaphthyl 湘潭大学 2023-08-22 CN disclosed
CN-112920813-A Photo-thermal responsive chiral photosensitive liquid crystal dopant containing azobenzene binaphthalene 湘潭大学 2021-06-08 CN disclosed
US-9249257-B2 Copolymer, organic semiconductor material, organic electrical device, photovoltaic module MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-9212254-B2 2015-12-15 US disclosed
EP-2857429-A1 COPOLYMER, ORGANIC SEMICONDUCTOR MATERIAL, ORGANIC ELECTRICAL DEVICE, AND SOLAR CELL MODULE Mitsubishi Chemical Corporation (JP) 2015-04-08 EP disclosed
US-20150094436-A1 COPOLYMER, ORGANIC SEMICONDUCTOR MATERIAL, ORGANIC ELECTRICAL DEVICE, AND PHOTOVOLTAIC MODULE MITSUBISHI CHEMICAL CORPORATION (JP) 2015-04-02 US disclosed
CN-104350082-A Copolymer, organic semiconductor material, organic electronic device, and solar cell module MITSUBISHI CHEM CORP 2015-02-11 CN disclosed
EP-2138545-B1 USE OF PORPHYRAZINE DERIVATIVE AS SEMICONDUCTOR UNIV HIROSHIMA (JP) 2014-01-08 EP disclosed
EP-2664655-A1 Novel synthesis for 5-alkyl-2,3-dihalogenthiophenes Hiroshima University (JP) 2013-11-20 EP disclosed
EP-2138545-A1 NOVEL PORPHYRAZINE DERIVATIVE AND INTERMEDIATE THEREOF, METHOD FOR PRODUCTION OF NOVEL PORPHYRAZINE DERIVATIVE AND INTERMEDIATE THEREOF, AND USE OF PORPHYRAZINE DERIVATIVE Hiroshima University (JP) 2009-12-30 EP disclosed
US-5260294-A Treatment of diseases caused by oxidative metabolism of arachidonic acid; antiinflammatory, antiallergins, antiarthriric HOFFMAN-LA ROCHE INC. (US) 1993-11-09 US disclosed
US-5132310-A Benzochroman compounds, lipoxygenase inhibitors HOFFMANN-LA ROCHE INC. (US) 1992-07-21 US disclosed
US-5015661-A Lipoxygenase inhibitors HOFFMANN-LA ROCHE INC. (US) 1991-05-14 US disclosed
EP-0354508-A2 Benzopyranol derivatives F. HOFFMANN-LA ROCHE AG (CH) 1990-02-14 EP disclosed