Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122066 | 1.00 | KDM4E (0.40) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL1756488 | 1.00 | KDM4E (0.40) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL3076471 | 1.00 | KDM4E (0.40) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL1304794 | 1.00 | KDM4E (0.40) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL15791269 | 1.00 | KDM4E (0.40) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL3877421 | 1.00 | KDM4E (0.40) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL3357183 | 0.98 | TDP1 (0.41) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL3870601 | 0.92 | KDM4E (0.42) | KDM4ETDP1ALDH1A1HSD17B10POLB | |
| SCHEMBL10005497 | 0.89 | KDM4E (0.36) | KDM4ETDP1ESR1ADRA2AADORA3 | |
| SCHEMBL21980888 | 0.89 | KDM4E (0.36) | KDM4ETDP1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106536528-B | Polycyclic polymers based on tetra-heteroaryl indacenodithiophenes and their use | 默克专利股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| US-9914742-B2 | Tetra-heteroaryl indacenodithiophene-based polycyclic polymers and their use | MERCK PATENT GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-9914742-B2 | Tetra-heteroaryl indacenodithiophene-based polycyclic polymers and their use | MERCK PATENT GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-9914742-B2 | Tetra-heteroaryl indacenodithiophene-based polycyclic polymers and their use | MERCK PATENT GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-20170210752-A1 | TETRA-HETEROARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE | MERCK PATENT GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210752-A1 | TETRA-HETEROARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE | MERCK PATENT GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210752-A1 | TETRA-HETEROARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE | MERCK PATENT GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| EP-3174915-A1 | TETRA-HETEROARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE | Merck Patent GmbH (DE) | 2017-06-07 | — | — | EP | disclosed |
| CN-106536528-A | Polycyclic polymers based on tetra-heteroaryl indacenodithiophenes and their use | 默克专利股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| WO-2016015804-A1 | TETRA-HETEROARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
| WO-2016015804-A1 | TETRA-HETEROARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
| EP-2138545-B1 | USE OF PORPHYRAZINE DERIVATIVE AS SEMICONDUCTOR | UNIV HIROSHIMA (JP) | 2014-01-08 | — | — | EP | disclosed |
| EP-2664655-A1 | Novel synthesis for 5-alkyl-2,3-dihalogenthiophenes | Hiroshima University (JP) | 2013-11-20 | — | — | EP | disclosed |
| EP-2138545-A1 | NOVEL PORPHYRAZINE DERIVATIVE AND INTERMEDIATE THEREOF, METHOD FOR PRODUCTION OF NOVEL PORPHYRAZINE DERIVATIVE AND INTERMEDIATE THEREOF, AND USE OF PORPHYRAZINE DERIVATIVE | Hiroshima University (JP) | 2009-12-30 | — | — | EP | disclosed |
| US-20070287848-A1 | Silicon Compound Containi-Electron Conjugated-System Molecule and Process for Producing the Same | SHARP KABUSHIKI KAISHA (JP) | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287848-A1 | Silicon Compound Containi-Electron Conjugated-System Molecule and Process for Producing the Same | SEM1, F12, ESPL1 | KDM4E 2479/4885TDP1 3768/4885ESR1 9/4885 |
| US-20170210752-A1 | TETRA-HETEROARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE | TERT, ICMT, TEC | KDM4E 2373/4885TDP1 1836/4885ESR1 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.