Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19152761 | 0.75 | OPRM1 (0.49) | OPRM1OPRL1 | |
| SCHEMBL22540261 | 0.75 | OPRM1 (0.46) | OPRM1OPRL1 | |
| SCHEMBL21766728 | 0.72 | OPRL1 (0.52) | OPRM1OPRL1 | |
| SCHEMBL19153406 | 0.71 | OPRM1 (0.53) | OPRM1OPRL1 | |
| SCHEMBL19153829 | 0.68 | OPRM1 (0.50) | OPRM1OPRL1 | |
| SCHEMBL23316766 | 0.67 | OPRL1 (0.42) | OPRM1OPRL1 | |
| SCHEMBL19153839 | 0.67 | OPRM1 (0.49) | OPRM1OPRL1 | |
| SCHEMBL21766651 | 0.67 | OPRL1 (0.49) | OPRM1OPRL1 | |
| SCHEMBL22222298 | 0.66 | GRIN2D (0.50) | OPRM1OPRL1 | |
| SCHEMBL19148732 | 0.66 | OPRM1 (0.54) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3722283-A1 | 3-(CARBOXYETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2020-10-14 | — | — | EP | disclosed |