Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546301 | 0.78 | TYMS (0.52) | NPC1RAB9AALDH1A1HPGDGAA | |
| SCHEMBL14399071 | 0.78 | KMT2A (0.53) | CACNA1HNPC1RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28952652 | 0.77 | KMT2A (0.56) | CACNA1HNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8502483 | 0.76 | MAPT (0.45) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12892268 | 0.75 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8502481 | 0.75 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8502457 | 0.75 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20867740 | 0.75 | IDO1 (0.57) | CACNA1HALDH1A1DDAH1KDM4EPOLB | |
| SCHEMBL17513343 | 0.75 | CACNA1H (0.50) | CACNA1HNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4151145 | 0.75 | TDP1 (0.51) | CACNA1HNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210831-A1 | INHIBITORS OF CD40-CD154 BINDING | TONIX Pharmaceuticals Holding Corp (US) | 2020-10-15 | — | — | WO | disclosed |