Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502483 | 0.80 | MAPT (0.45) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL12892268 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL11546301 | 0.79 | TYMS (0.52) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL8502457 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL4386728 | 0.76 | KMT2A (0.44) | ALDH1A1HPGDGAAMAPTHSD17B10 | |
| SCHEMBL14820402 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL22545554 | 0.75 | CACNA1H (0.46) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL13733049 | 0.73 | CYP1A2 (0.51) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL4794109 | 0.72 | F7 (0.44) | ALDH1A1HPGDKDM4EMAPTTSHR | |
| SCHEMBL28601622 | 0.72 | MEN1 (0.30) | ALDH1A1KDM4EMAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |