Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22874820 | 0.77 | — | — | |
| SCHEMBL24837676 | 0.77 | — | — | |
| SCHEMBL22722883 | 0.76 | TSHR (0.38) | — | |
| SCHEMBL24219555 | 0.76 | — | — | |
| SCHEMBL22875125 | 0.74 | KDM4E (0.30) | — | |
| SCHEMBL6602752 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL22969999 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL22875126 | 0.73 | ACHE (0.32) | — | |
| SCHEMBL22874821 | 0.73 | — | — | |
| SCHEMBL24139224 | 0.73 | HTT (0.33) | GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210630-A1 | TRICYCLIC DEGRADERS OF IKAROS AND AIOLOS | C4 THERAPEUTICS, INC. (US) | 2020-10-15 | — | — | WO | disclosed |