SCHEMBL22550672

SCHEMBL22550672

CCCCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)C(NC(=O)[C@@H](C)NC(=O)CCOCCOCCOCCOCCOCCNC(=O)CCCC[C@@H]1SC[C@H]2NC(=O)N[C@@H]12)[C@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)NC(C(=O)N[C@H](CCC(=O)O)C(=O)N[C@@H](C)C(N)=O)[C@@H](C)O

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 11/20 0.54
▸ PLG P00747 1/20 0.52
▸ PRSS1 P07477 1/20 0.52
▸ PRSS2 P07478 1/20 0.52
▸ PRSS3 P35030 1/20 0.52
▸ TPSAB1 Q15661 1/20 0.52
▸ TFPI P10646 1/20 0.49
▸ RAMP3 O60896 2/20 0.49
▸ CALCR P30988 2/20 0.49
▸ GCGR P47871 1/20 0.49
▸ IL23R Q5VWK5 4/20 0.48
▸ SCTR P47872 1/20 0.47
▸ CCKBR P32239 1/20 0.47
▸ OPRM1 P35372 1/20 0.46
▸ OPRD1 P41143 1/20 0.46
▸ OPRK1 P41145 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24089915 0.88 GLP1R (0.51) GLP1RTFPIRAMP3CALCRGCGR
SCHEMBL22550645 0.84 PLG (0.57) GLP1RPLGPRSS1PRSS2PRSS3
SCHEMBL22550671 0.82 RAMP3 (0.53) GLP1RPLGPRSS1PRSS2PRSS3
SCHEMBL22550646 0.79 RAMP3 (0.53) GLP1RRAMP3CALCR
SCHEMBL22803203 0.78 PLG (0.53) PLGPRSS1PRSS2PRSS3TPSAB1
SCHEMBL24089913 0.77 GLP1R (0.46) GLP1RPLGPRSS1PRSS2PRSS3
SCHEMBL30313496 0.77 CASP3 (0.47) GLP1RPLGPRSS1PRSS2PRSS3
SCHEMBL22423719 0.75 RAMP3 (0.56) GLP1RTFPIRAMP3CALCRGCGR
SCHEMBL30812508 0.75 IL23R (0.58) GLP1RIL23R
SCHEMBL21168599 0.75 GLP1R (0.52) GLP1RTFPIGCGRIL23ROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200323973-A1 EPITOPE-TARGETED PEPTIDE IMMUNOSTIMULANTS INSTITUTE FOR SYSTEMS BIOLOGY 2020-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200323973-A1 EPITOPE-TARGETED PEPTIDE IMMUNOSTIMULANTS MICA, ICOS, CD47 GLP1R 802/4885PLG 2137/4885PRSS1 2036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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