Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 5/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | TFPI | P10646 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.49 |
| ▸ | MAFG | O15525 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790633 | 0.85 | TFPI (0.60) | GLP1RTFPIGCGR | |
| SCHEMBL30439703 | 0.80 | GLP1R (0.53) | GLP1RAKT1MAFGGCGR | |
| SCHEMBL18239361 | 0.80 | AKT1 (0.54) | GLP1RAKT1GCGR | |
| SCHEMBL3805702 | 0.76 | RAMP3 (0.55) | TFPI | |
| SCHEMBL22423719 | 0.75 | RAMP3 (0.56) | GLP1RTFPIGCGRIL23R | |
| SCHEMBL22550672 | 0.75 | GLP1R (0.54) | GLP1RTFPIGCGRIL23ROPRM1 | |
| SCHEMBL30439960 | 0.74 | C5AR1 (0.57) | GLP1RGCGROPRM1OPRD1OPRK1 | |
| SCHEMBL30440029 | 0.74 | C5AR1 (0.59) | GLP1RAKT1IL23R | |
| SCHEMBL30439872 | 0.74 | C5AR1 (0.60) | GLP1RGCGROPRD1 | |
| SCHEMBL30313496 | 0.74 | CASP3 (0.47) | GLP1RAKT1TFPIPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190216893-A1 | COMPOSITIONS AND METHODS OF MODULATING IMMUNE RESPONSE | THE SCRIPPS RESEARCH INSTITUTE | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190216893-A1 | COMPOSITIONS AND METHODS OF MODULATING IMMUNE RESPONSE | IFNG, MYD88, ICOS | GLP1R 3752/4885AKT1 863/4885TFPI 3169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.