Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551031 | 1.00 | MBOAT4 (0.39) | MBOAT4LMNATSHRSMN1; SMN2TLR9 | |
| SCHEMBL22551038 | 1.00 | MBOAT4 (0.39) | MBOAT4LMNATSHRSMN1; SMN2TLR9 | |
| SCHEMBL20011994 | 0.89 | HRH2 (0.38) | MBOAT4LMNATSHRSMN1; SMN2 | |
| SCHEMBL21853865 | 0.89 | HRH2 (0.38) | MBOAT4LMNATSHRSMN1; SMN2 | |
| SCHEMBL21853866 | 0.89 | HRH2 (0.38) | MBOAT4LMNATSHRSMN1; SMN2 | |
| SCHEMBL20012410 | 0.88 | SMN1; SMN2 (0.39) | LMNATSHRSMN1; SMN2TLR9TLR8 | |
| SCHEMBL22551039 | 0.87 | CCR1 (0.45) | MAPK11MAPK14CCR1 | |
| SCHEMBL20011995 | 0.87 | PRMT5 (0.42) | LMNATSHRSMN1; SMN2MAPK11MAPK14 | |
| SCHEMBL20012185 | 0.86 | CYP3A4 (0.44) | LMNATSHRSMN1; SMN2MAPK11MAPK14 | |
| SCHEMBL21853834 | 0.84 | ALDH1A1 (0.40) | LMNATSHRSMN1; SMN2MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515903-B1 | PREPARATION AND USES OF PYRIMIDINONE DERIVATIVES | CANCER RESEARCH TECH LTD (GB) | 2020-10-21 | — | — | EP | claimed |