Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | HTR1F | P30939 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551204 | 0.91 | FGFR1 (0.60) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL22551239 | 0.91 | FGFR1 (0.56) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL29568146 | 0.91 | FGFR1 (0.60) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL29568745 | 0.91 | FGFR1 (0.56) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL22551232 | 0.89 | FGFR1 (0.65) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL29568635 | 0.89 | FGFR1 (0.65) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL22551168 | 0.89 | FGFR1 (0.59) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL29568126 | 0.89 | FGFR1 (0.59) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| Acetic Acid SCHEMBL31561387 | 0.88 | FGFR1 (0.58) | FGFR1HDAC3HDAC1HDAC2HDAC4 | |
| SCHEMBL22551227 | 0.87 | FGFR1 (0.54) | FGFR1HDAC3HDAC1HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725777-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2020-10-21 | — | — | EP | claimed |