Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 13/20 | 0.65 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551232 | 1.00 | FGFR1 (0.65) | FGFR1EGFRHDAC6HDAC3HDAC4 | |
| SCHEMBL22551202 | 0.89 | FGFR1 (0.57) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL29568745 | 0.88 | FGFR1 (0.56) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL29568146 | 0.88 | FGFR1 (0.60) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22551239 | 0.88 | FGFR1 (0.56) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22551204 | 0.88 | FGFR1 (0.60) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22551168 | 0.86 | FGFR1 (0.59) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL29568126 | 0.86 | FGFR1 (0.59) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| Acetic Acid SCHEMBL31561387 | 0.86 | FGFR1 (0.58) | FGFR1HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL22551227 | 0.85 | FGFR1 (0.54) | FGFR1HDAC6HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956315-B1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech Srl (IT) | 2025-04-16 | — | — | EP | claimed |
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | claimed |
| EP-3956315-A1 | BENZO- AND PYRIDO-PYRAZOLES AS PROTEIN KINASE INHIBITORS | Rottapharm Biotech S.r.l. (IT) | 2022-02-23 | — | — | EP | disclosed |