Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | XPO1 | O14980 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928750 | 0.83 | RAB9A (0.58) | RAB9APTGS1NPC1CNR1CNR2 | |
| SCHEMBL1465583 | 0.81 | RAB9A (0.57) | RAB9APTGS1NPC1CNR1CNR2 | |
| SCHEMBL2259495 | 0.79 | RAB9A (0.49) | RAB9APTGS1NPC1CNR1CNR2 | |
| SCHEMBL1621494 | 0.79 | RAB9A (0.52) | RAB9APTGS1NPC1CNR1CNR2 | |
| SCHEMBL2256509 | 0.79 | NPY5R (0.53) | RAB9APTGS1NPC1CNR1CNR2 | |
| SCHEMBL9893012 | 0.79 | RAB9A (0.57) | RAB9APTGS1NPC1GAANPY5R | |
| SCHEMBL15219103 | 0.78 | GAA (0.48) | RAB9APTGS1NPC1CNR1CNR2 | |
| SCHEMBL14960340 | 0.78 | RAB9A (0.53) | RAB9APTGS1NPC1CNR1CNR2 | |
| SCHEMBL2252774 | 0.77 | RAB9A (0.50) | RAB9APTGS1NPC1GAANPY5R | |
| SCHEMBL2254610 | 0.77 | RAB9A (0.50) | RAB9APTGS1NPC1GAANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957063-B2 | Amine and ether compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2015-02-17 | — | — | US | disclosed |
| US-8957063-B2 | Amine and ether compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2015-02-17 | — | — | US | disclosed |
| US-8957063-B2 | Amine and ether compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2015-02-17 | — | — | US | disclosed |
| EP-2265585-B1 | AMINE AND ETHER COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2014-09-17 | — | — | EP | disclosed |
| EP-2265585-B1 | AMINE AND ETHER COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2014-09-17 | — | — | EP | disclosed |
| US-20110190256-A1 | Amine and Ether Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110190256-A1 | Amine and Ether Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110190256-A1 | Amine and Ether Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | US | disclosed |
| WO-2009105509-A1 | AMINE AND ETHER COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190256-A1 | Amine and Ether Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, GPR18 | RAB9A 2591/4885PTGS1 430/4885NPC1 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.