SCHEMBL22552555

SCHEMBL22552555

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nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.57
▸ KDM4E B2RXH2 1/20 0.57
▸ CYP2D6 P10635 1/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ HK2 P52789 5/20 0.52
▸ HK1 P19367 4/20 0.52
▸ PYGB P11216 7/20 0.46
▸ GAA P10253 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.40
▸ THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18467702 1.00 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL15966274 1.00 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL12190147 1.00 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL15965658 1.00 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL29532523 1.00 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19HK2
N-Acetylglucosamine SCHEMBL19423349 0.92 MAPK1 (0.56) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL24252744 0.86 KDM4E (0.55) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL24141320 0.86 LMNA (0.55) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL14520983 0.86 LMNA (0.55) LMNAKDM4ECYP2D6CYP2C19HK2
SCHEMBL23880301 0.86 PYGB (0.64) LMNAKDM4ECYP2D6CYP2C19HK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250275993-A1 GLYCOSYLATION INHIBITORS AS THERAPEUTICS FOR STROKE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-09-04 — — US disclosed
CN-119300837-A Glycosylation inhibitors as therapeutic agents for stroke 加利福尼亚大学董事会 2025-01-10 — — CN disclosed
US-20240084352-A1 MICROBIAL POLYSACCHARIDES AND METHODS OF USE MORGAN STATE UNIV (US) 2024-03-14 — — US disclosed
US-20200332335-A1 MICROBIAL POLYSACCHARIDES AND METHODS OF USE MORGAN STATE UNIVERSITY 2020-10-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240084352-A1 MICROBIAL POLYSACCHARIDES AND METHODS OF USE NANS, GMDS, SIGLEC7 LMNA 1866/4885KDM4E 4621/4885CYP2D6 3346/4885
US-20200332335-A1 MICROBIAL POLYSACCHARIDES AND METHODS OF USE NANS, GMDS, SIGLEC7 LMNA 1866/4885KDM4E 4621/4885CYP2D6 3346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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