Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22570499 | 1.00 | TSHR (0.45) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22570500 | 1.00 | TSHR (0.45) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22570546 | 1.00 | TSHR (0.45) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22570559 | 1.00 | TSHR (0.45) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22570503 | 0.98 | TSHR (0.44) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22570498 | 0.98 | TSHR (0.44) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22553042 | 0.98 | TSHR (0.44) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22570619 | 0.98 | TSHR (0.44) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22570539 | 0.98 | TSHR (0.44) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL22553041 | 0.97 | HDAC4 (0.43) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961178-B2 | Cycloaddition reactions using quantum dots | NORTHWESTERN UNIVERSITY (US) | 2021-03-30 | — | — | US | disclosed |
| US-20200331836-A1 | CYCLOADDITION REACTIONS USING QUANTUM DOTS | NORTHWESTERN UNIVERSITY | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331836-A1 | CYCLOADDITION REACTIONS USING QUANTUM DOTS | SYNGR2, SYNJ1, SQLE | TSHR 3658/4885DAO 2116/4885NAPRT 1584/4885 |
| US-10961178-B2 | Cycloaddition reactions using quantum dots | SYNGR2, SYNJ1, SQLE | TSHR 3658/4885DAO 2116/4885NAPRT 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.