SCHEMBL22555331

SCHEMBL22555331

CO[Si](OC)(OC)C(CC(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
ALOX15 P16050 1/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
FOLH1 Q04609 2/20 0.32
MAPT P10636 1/20 0.31
GABRR1 P24046 2/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27959244 0.79 MEN1 (0.35) TDP1ALOX15MAPTALDH1A1LMNA
SCHEMBL1971029 0.79 CA2 (0.32) TDP1
SCHEMBL22555513 0.78 CYP1A2 (0.45) FOLH1
SCHEMBL27959251 0.78 MGAM (0.40) TDP1SMN1; SMN2ALOX15ALDH1A1LMNA
SCHEMBL28165475 0.76 CHRM1 (0.44) TDP1MAPT
SCHEMBL5003457 0.73 TDP1 (0.43) TDP1SMN1; SMN2ALOX15SLC22A6FOLH1
SCHEMBL4319153 0.73 TDP1 (0.43) TDP1SMN1; SMN2ALOX15SLC22A6FOLH1
SCHEMBL19410648 0.72 CA2 (0.45) TDP1MAPT
SCHEMBL19410733 0.71 GPR84 (0.47) MAPT
SCHEMBL4531065 0.70 GPR84 (0.50) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11203670-B2 Bissilylamino group-containing organic polysilazane compound, method for producing same, and composition containing same and cured product SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-12-21 US disclosed
EP-3730538-B1 BISSILYLAMINO GROUP-CONTAINING ORGANIC POLYSILAZANE COMPOUND, METHOD FOR PRODUCING SAME, AND COMPOSITION CONTAINING SAME AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2021-09-08 EP disclosed
EP-3730538-A1 BISSILYLAMINO GROUP-CONTAINING ORGANIC POLYSILAZANE COMPOUND, METHOD FOR PRODUCING SAME, AND COMPOSITION CONTAINING SAME AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2020-10-28 EP disclosed
US-20200332070-A1 BISSILYLAMINO GROUP-CONTAINING ORGANIC POLYSILAZANE COMPOUND, METHOD FOR PRODUCING SAME, AND COMPOSITION CONTAINING SAME AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-10-22 US disclosed