SCHEMBL2255605

SCHEMBL2255605

C[SiH](C)OC([O])CC(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2256664 0.76
SCHEMBL1748644 0.75
SCHEMBL4190582 0.70
SCHEMBL1723602 0.70
SCHEMBL4842476 0.70
SCHEMBL573169 0.70
SCHEMBL7520133 0.69
SCHEMBL9428144 0.67
SCHEMBL4188553 0.66 ALDH1A1 (0.33)
SCHEMBL8136671 0.63 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3539968-B1 NOVEL TRITYL PROTECTING AGENT SEKISUI MEDICAL CO LTD (JP) 2021-07-14 EP claimed
US-10981940-B2 Trityl protecting agent SEKISUl MEDICAL CO., LTD. (JP) 2021-04-20 US claimed
US-20190308997-A1 NOVEL TRITYL PROTECTING AGENT SEKISUI MEDICAL CO., LTD. (JP) 2019-10-10 US claimed
EP-3539968-A1 NOVEL TRITYL PROTECTING AGENT Sekisui Medical Co., Ltd. (JP) 2019-09-18 EP claimed
CN-109963861-B Novel trityl protective agent 积水医疗株式会社 2021-09-28 CN disclosed
EP-3539968-B1 NOVEL TRITYL PROTECTING AGENT SEKISUI MEDICAL CO LTD (JP) 2021-07-14 EP disclosed
US-10981940-B2 Trityl protecting agent SEKISUl MEDICAL CO., LTD. (JP) 2021-04-20 US disclosed
US-20190308997-A1 NOVEL TRITYL PROTECTING AGENT SEKISUI MEDICAL CO., LTD. (JP) 2019-10-10 US disclosed
EP-3539968-A1 NOVEL TRITYL PROTECTING AGENT Sekisui Medical Co., Ltd. (JP) 2019-09-18 EP disclosed
US-9073885-B2 Vitamin D3 lactone derivatives TEIJIN PHARMA LIMITED (JP) 2015-07-07 US disclosed
EP-1589009-B1 VITAMIN D3 LACTONE DERIVATIVE TEIJIN PHARMA LTD (JP) 2014-10-08 EP disclosed
EP-2363390-A1 DERIVED LACTAM FROM D3 VITAMIN Teijin Pharma Limited (JP) 2011-09-07 EP disclosed
US-20110207944-A1 VITAMIN D3 LACTAM DERIVATIVE TEIJIN PHARMA LIMITED (JP) 2011-08-25 US disclosed
US-20060148768-A1 Vitamin d3 lactone derivatives TEIJIN LIMITED (JP) 2006-07-06 US disclosed
EP-1589009-A1 VITAMIN D3 LACTONE DERIVATIVE Teijin Pharma Limited (JP) 2005-10-26 EP disclosed