Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287991 | 0.88 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| SCHEMBL11877966 | 0.78 | KDM4E (0.49) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| SCHEMBL542583 | 0.78 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| SCHEMBL702800 | 0.78 | CYP3A4 (0.46) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| SCHEMBL21495073 | 0.78 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| SCHEMBL4420495 | 0.78 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| SCHEMBL11800360 | 0.77 | SLC6A2 (0.48) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| Bromide SCHEMBL22094891 | 0.77 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| Bromide SCHEMBL1696091 | 0.77 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E | |
| SCHEMBL9185638 | 0.75 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874722-B | Moisture-heat-resistant epoxy conductive adhesive, preparation method and application thereof | 东莞市德聚胶接技术有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-114874722-A | Moisture-heat-resistant epoxy conductive adhesive, preparation method and application thereof | 东莞市德聚胶接技术有限公司 | 2022-08-09 | — | — | CN | claimed |
| EP-1738646-B1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON INC (US) | 2013-03-20 | — | — | EP | claimed |
| US-7291649-B2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-11-06 | — | — | US | claimed |
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. | 2007-01-04 | — | — | US | claimed |
| EP-1738646-A2 | Forming germicidal aromatic dialdehydes with acetals | ETHICON, INC. (US) | 2007-01-03 | — | — | EP | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-114874722-A | Moisture-heat-resistant epoxy conductive adhesive, preparation method and application thereof | 东莞市德聚胶接技术有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111499865-B | Synthesis method of phosphorus-containing polyimide | 湘潭大学 | 2022-04-26 | — | — | CN | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| US-20210369716-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2021-12-02 | — | — | US | disclosed |
| US-20210369716-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | NOVARTIS AG (CH) | 2021-12-02 | — | — | US | disclosed |
| US-11123348-B2 | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG (CH) | 2021-09-21 | — | — | US | disclosed |
| EP-1296981-A2 | SUBSTITUTED PYRROLOPYRIDINONE DERIVATIVES USEFUL AS PHOSPHODIESTERASE INHIBITORS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| US-20020010183-A1 | Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2002-01-24 | — | — | US | disclosed |
| WO-2001087882-A2 | SUBSTITUTED PYRROLOPYRIDINONE DERIVATIVES USEFUL AS PHOSPHODIESTERASE INHIBITORS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2000018776-A1 | DIMERIC DIIMINE TRANSITION METAL COMPLEX AND CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2000-04-06 | — | — | WO | disclosed |
| US-4310670-A | Low-temperature, aqueous conversion of 4-picoline derivative to 5-cyano-[3,4'-bipyridin]-6(1H)-one | STERLING DRUG INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-4264609-A | N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic | STERLING DRUG INC. (US) | 1981-04-28 | — | — | US | disclosed |
| US-4223149-A | Process for producing 3-cyano-5-(pyridinyl)-2(1H)-pyridinones | STERLING DRUG INC. (US) | 1980-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004808-A1 | Forming germicidal aromatic dialdehydes with acetals | ALPG, DDT, ACR | SLC6A3 3382/4885SLC6A2 4589/4885SLC6A4 4599/4885 |
| US-11123348-B2 | Compounds and compositions for the treatment of parasitic diseases | TYR, TBCA, MAPT | SLC6A3 736/4885SLC6A2 105/4885SLC6A4 993/4885 |
| US-20020010183-A1 | Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors | PDE5A, PDE3A, PDE3B | SLC6A3 1227/4885SLC6A2 1836/4885SLC6A4 2697/4885 |
| US-20210369716-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | TYR, TBCA, MAPT | SLC6A3 736/4885SLC6A2 105/4885SLC6A4 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.