Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556898 | 0.87 | MAPT (0.39) | MAPTGPR174ALDH1A1SRD5A2LMNA | |
| SCHEMBL22556761 | 0.82 | SRD5A2 (0.42) | MAPTSRD5A2MTNR1B | |
| SCHEMBL28465448 | 0.82 | MAPT (0.45) | MAPTGPR174ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22579458 | 0.81 | SRD5A2 (0.42) | MAPTALDH1A1SRD5A2LMNAMTNR1B | |
| SCHEMBL22556698 | 0.80 | GPR174 (0.39) | MAPTGPR174ALDH1A1SRD5A2LMNA | |
| SCHEMBL22579361 | 0.76 | HTR2C (0.37) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL22556822 | 0.75 | HTR2C (0.36) | MAPTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL1865742 | 0.72 | SRD5A2 (0.41) | MAPTGPR174ALDH1A1SRD5A2LMNA | |
| SCHEMBL22579381 | 0.71 | NPC1 (0.38) | MAPTALDH1A1SRD5A2LMNAMTNR1B | |
| SCHEMBL22556778 | 0.70 | MAPT (0.43) | MAPTGPR174ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825654-A | Phenylmethylene piperidine derivatives, preparation method, intermediates and uses thereof | 北京酷瓴生物技术有限公司 | 2020-10-27 | — | — | CN | disclosed |
| WO-2020211836-A1 | BENZENE PIPERIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF AND USE THEREOF | 北京酷瓴生物技术有限公司 | 2020-10-22 | — | — | WO | disclosed |
| WO-2020211836-A1 | BENZENE PIPERIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF AND USE THEREOF | 北京酷瓴生物技术有限公司 | 2020-10-22 | — | — | WO | disclosed |