⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975753 | 0.80 | — | — | |
| SCHEMBL229792 | 0.79 | TSHR (0.50) | — | |
| SCHEMBL72471 | 0.79 | LMNA (0.62) | — | |
| SCHEMBL3898613 | 0.78 | — | — | |
| SCHEMBL11160110 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL128684 | 0.77 | — | — | |
| SCHEMBL31402602 | 0.77 | LMNA (0.60) | — | |
| SCHEMBL18152012 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL28875912 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL28727541 | 0.77 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149344-A1 | BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1-RELATED RETINOPATHIES | UNIVERSITÄT REGENSBURG (AT) | 2023-05-18 | — | — | US | claimed |
| EP-4125866-A1 | BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1 -RELATED RETINOPATHIES | Universität Regensburg (DE) | 2023-02-08 | — | — | EP | claimed |
| CN-115335045-A | Mutant bestrophin 1 modulators for the treatment of BEST 1-related retinopathy | 雷根斯堡大学 | 2022-11-11 | — | — | CN | claimed |
| WO-2021198254-A1 | BIOCHANIN A DERIVATIVES FOR TREATMENT OF BEST1 -RELATED RETINOPATHIES | UNIVERSITÄT REGENSBURG (DE) | 2021-10-07 | — | — | WO | claimed |
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | claimed |
| EP-3424926-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINS, THEIR PRODUCTION AND UTILISATION AS MEDICINE | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2019-01-09 | — | — | EP | claimed |
| EP-2609094-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| EP-3241829-A1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2017-11-08 | — | — | EP | claimed |
| US-20150351403-A1 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-12-10 | — | — | US | claimed |
| US-9006266-B2 | Heteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | claimed |
| EP-1532149-A2 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-05-25 | — | — | EP | claimed |
| US-20040097510-A1 | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-20 | — | — | US | claimed |
| WO-2004018468-A2 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PRODUCTION THEREOF AND THE USE OF THE SAME AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-04 | — | — | WO | claimed |
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | claimed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | claimed |
| EP-1330443-A1 | SUBSTITUTED PHENYLURACILS | Bayer CropScience AG (DE) | 2003-07-30 | — | — | EP | claimed |
| CN-1420873-A | Substituted phenyluracils | BAYER AG (DE) | 2003-05-28 | — | — | CN | claimed |
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | claimed |
| WO-2002034725-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2002-05-02 | — | — | WO | claimed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | claimed |