Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29568306 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1HPGDCHEK1MAPK10 | |
| SCHEMBL1552041 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDHSD17B10METAP2 | |
| SCHEMBL1911926 | 0.72 | NOS1 (0.59) | KDM4EALDH1A1HPGDCHEK1MAPK10 | |
| SCHEMBL29468200 | 0.72 | NOS1 (0.59) | KDM4EALDH1A1HPGDCHEK1MAPK10 | |
| SCHEMBL1008553 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDCHEK1AR | |
| SCHEMBL31014282 | 0.72 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDCHEK1AR | |
| SCHEMBL6127809 | 0.71 | MAPT (0.48) | KDM4EALDH1A1HPGDCHEK1MAPK10 | |
| SCHEMBL8404432 | 0.70 | AHR (0.47) | ALDH1A1CHEK1MAPK10RIPK1AR | |
| SCHEMBL15371410 | 0.69 | CCR8 (0.59) | KDM4EAHRHSD17B10KIF11TRIM24 | |
| SCHEMBL5583145 | 0.69 | MAPT (0.47) | ALDH1A1HPGDCHEK1MAPK10RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220248678-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-08-11 | — | — | US | disclosed |
| EP-3956337-A1 | HERBICIDAL COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-02-23 | — | — | EP | disclosed |
| CN-113498415-A | Herbicidal compounds | 先正达农作物保护股份公司 | 2021-10-12 | — | — | CN | disclosed |
| WO-2020212272-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220248678-A1 | HERBICIDAL COMPOUNDS | DDT, NOTUM, HACL2 | KDM4E 1444/4885ALDH1A1 106/4885HPGD 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.