SCHEMBL22557730

SCHEMBL22557730

C=CCOP(=O)([O-])c1c[n+](C)nc2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.32
▸ ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29568763 1.00 MAPT (0.32) MAPTATM
SCHEMBL22345432 0.80 POLB (0.31) —
SCHEMBL22345540 0.75 — —
SCHEMBL22345428 0.74 DDAH1 (0.30) —
Iodide SCHEMBL22345479 0.71 KMT2A (0.34) MAPT
SCHEMBL22345529 0.69 MEN1 (0.33) —
SCHEMBL22345526 0.66 NPY5R (0.43) MAPT
Iodide SCHEMBL22345589 0.65 NPY5R (0.42) MAPT
SCHEMBL22345536 0.65 NR1I2 (0.37) MAPT
SCHEMBL9940137 0.65 PKM (0.45) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220248678-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-08-11 — — US disclosed
EP-3956337-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-02-23 — — EP disclosed
WO-2020212272-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220248678-A1 HERBICIDAL COMPOUNDS DDT, NOTUM, HACL2 MAPT 3841/4885ATM 4268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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