Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2502851 | 0.83 | CA12 (0.48) | CA12CA1CA2CA3CA4 | |
| SCHEMBL30584970 | 0.80 | NQO2 (0.39) | CA12CA1CA2CA3CA4 | |
| SCHEMBL29272764 | 0.79 | ALDH1A1 (0.34) | KMT2AALDH1A1MAPTHPGDHTT | |
| SCHEMBL4639550 | 0.78 | CA12 (0.61) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11479346 | 0.78 | CA12 (0.59) | CA12CA1CA2CA3CA4 | |
| SCHEMBL31515128 | 0.77 | NQO2 (0.46) | CA12CA1CA2CA3CA4 | |
| SCHEMBL31515130 | 0.77 | NQO2 (0.46) | CA12CA1CA2CA3CA4 | |
| Water SCHEMBL2505335 | 0.76 | CA12 (0.44) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9450677 | 0.74 | TSHR (0.50) | CA12CA1CA2CA3CA4 | |
| SCHEMBL4496856 | 0.74 | SLC9A1 (0.50) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193851-B1 | COMBINATION THERAPIES FOR TREATMENT OF CANCER | ARAXES PHARMA LLC (US) | 2020-10-21 | — | — | EP | disclosed |