Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CBLB | Q13191 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882334 | 0.83 | CBLB (0.33) | CBLBP2RX7 | |
| SCHEMBL25342297 | 0.67 | ALDH1A1 (0.35) | NOS2BRD4 | |
| SCHEMBL24993700 | 0.67 | — | — | |
| SCHEMBL6850310 | 0.65 | CYP3A4 (0.44) | P2RX7 | |
| SCHEMBL22547310 | 0.63 | NR1H2 (0.43) | IDO1 | |
| SCHEMBL22245518 | 0.62 | P2RX7 (0.30) | P2RX7 | |
| SCHEMBL22911355 | 0.61 | — | — | |
| SCHEMBL24928806 | 0.61 | — | — | |
| SCHEMBL20208535 | 0.61 | TSHR (0.31) | — | |
| SCHEMBL15288351 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725791-A1 | SALT SERVING AS AKT INHIBITOR AND CRYSTAL THEREOF | Harbin Zhenbao Pharmaceutical Co., Ltd. (CN) | 2020-10-21 | — | — | EP | disclosed |