SCHEMBL2256115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2256982	0.93	RXRA (0.50)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2260114	0.92	RXRA (0.49)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2257280	0.91	RXRA (0.46)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2257192	0.90	RXRA (0.43)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2257698	0.90	SYK (0.43)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2255719	0.90	KCNN4 (0.43)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2254939	0.89	RXRA (0.45)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2256887	0.89	SYK (0.42)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2256543	0.89	RXRA (0.45)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9
	SCHEMBL2258816	0.88	PTGS2 (0.49)	PTGS2PTGS1CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.