Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23193003 | 0.92 | FOLH1 (0.35) | FOLH1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL21137872 | 0.87 | HDAC3 (0.30) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL23193103 | 0.83 | FOLH1 (0.34) | FOLH1HDAC1HDAC6SIRT2OPRM1 | |
| SCHEMBL23193044 | 0.82 | FOLH1 (0.37) | FOLH1HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL22618762 | 0.82 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL22618791 | 0.80 | FOLH1 (0.34) | FOLH1OPRM1DGAT1SETD7 | |
| SCHEMBL23192990 | 0.80 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL22561476 | 0.80 | FOLH1 (0.34) | FOLH1OPRM1DRD2DGAT1 | |
| SCHEMBL22618763 | 0.79 | FOLH1 (0.34) | FOLH1OPRM1DGAT1 | |
| SCHEMBL27189806 | 0.77 | FOLH1 (0.34) | FOLH1HDAC1HDAC6HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725798-A1 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2020-10-21 | — | — | EP | disclosed |