Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22618762 | 0.94 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL23192990 | 0.92 | FOLH1 (0.32) | FOLH1 | |
| SCHEMBL23193003 | 0.84 | FOLH1 (0.35) | FOLH1OPRM1HDAC1SIRT2HDAC6 | |
| SCHEMBL22561392 | 0.83 | FOLH1 (0.36) | FOLH1OPRM1HDAC1SIRT2HDAC6 | |
| SCHEMBL22561476 | 0.80 | FOLH1 (0.34) | FOLH1OPRM1 | |
| SCHEMBL22618763 | 0.79 | FOLH1 (0.34) | FOLH1OPRM1 | |
| SCHEMBL22618791 | 0.79 | FOLH1 (0.34) | FOLH1OPRM1 | |
| SCHEMBL23193044 | 0.76 | FOLH1 (0.37) | FOLH1HDAC1SIRT2HDAC6 | |
| SCHEMBL25100412 | 0.75 | FOLH1 (0.39) | FOLH1SIRT2 | |
| SCHEMBL27189806 | 0.75 | FOLH1 (0.34) | FOLH1OPRM1HDAC1SIRT2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210101906-A2 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101906-A2 | BIOACTIVE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | DOCK11, PAICS, RHOA | FOLH1 207/4885OPRM1 4247/4885HDAC1 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.