Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.32 |
| ▸ | NMT2 | O60551 | 1/20 | 0.32 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561476 | 0.92 | FOLH1 (0.34) | FOLH1DGAT1NMT2NMT1CCKAR | |
| SCHEMBL22618763 | 0.91 | FOLH1 (0.34) | FOLH1DGAT1NMT2NMT1CCKAR | |
| SCHEMBL26603616 | 0.91 | FOLH1 (0.34) | FOLH1DGAT1NMT2NMT1SIRT2 | |
| SCHEMBL27189819 | 0.86 | NMT2 (0.33) | FOLH1NMT2NMT1HDAC3HDAC4 | |
| SCHEMBL27189815 | 0.82 | DGAT1 (0.35) | FOLH1DGAT1CCKARCCKBROPRM1 | |
| SCHEMBL23193195 | 0.81 | OPRM1 (0.34) | FOLH1SIRT2OPRM1MMP2MMP9 | |
| SCHEMBL22618791 | 0.79 | FOLH1 (0.34) | FOLH1DGAT1CCKARCCKBROPRM1 | |
| SCHEMBL27409838 | 0.78 | FOLH1 (0.31) | FOLH1OPRM1MMP2MMP9MMP8 | |
| SCHEMBL21137502 | 0.78 | MMP2 (0.30) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL22618790 | 0.78 | FOLH1 (0.30) | FOLH1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4349372-A1 | ANTIBODY DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |