SCHEMBL22561684

SCHEMBL22561684

Nc1nc2cc(Cl)cc(Cl)c2o1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52
THRB P10828 1/20 0.52
MAPK1 P28482 1/20 0.52
NUDT1 P36639 2/20 0.47
PIK3CG P48736 2/20 0.47
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
AHR P35869 3/20 0.36
ALDH1A1 P00352 2/20 0.35
GPR35 Q9HC97 2/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
CASP1 P29466 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18645373 0.81 NUDT1 (0.68) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL19922859 0.81 NUDT1 (0.44) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL10727909 0.79 AHR (0.38) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL22561760 0.77 NUDT1 (0.41) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL13903 0.77 NUDT1 (0.41) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL19939690 0.77 NUDT1 (0.45) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL11593571 0.76 KCNA3 (0.37) ALOX15MAPTLMNACA12CA1
SCHEMBL6010774 0.76 AHR (0.36) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL646762 0.76 AHR (0.36) ALOX15MAPTLMNACYP1A2THRB
SCHEMBL2245699 0.74 NPC1 (0.51) MAPTLMNAALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3725788-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES Bayer AG (DE) 2020-10-21 EP disclosed