Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.35 |
| ▸ | GABRP | O00591 | 5/20 | 0.35 |
| ▸ | GABRD | O14764 | 5/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561757 | 0.83 | KIF20B (0.38) | ALDH1A1KDM4EPOLBSMN1; SMN2MAPT | |
| SCHEMBL22561713 | 0.81 | NUDT1 (0.42) | NUDT1KDM4EMAPTLMNACYP1A2 | |
| SCHEMBL18935884 | 0.78 | HDAC6 (0.44) | ALDH1A1KDM4EPOLBCYP1A2KIF20B | |
| SCHEMBL22561684 | 0.77 | ALOX15 (0.52) | NUDT1ALDH1A1POLBMAPTLMNA | |
| SCHEMBL1025681 | 0.76 | NPC1 (0.45) | ALDH1A1MAPTKIF20BNPC1HTT | |
| SCHEMBL19922859 | 0.74 | NUDT1 (0.44) | NUDT1MAPTLMNACYP1A2THRB | |
| SCHEMBL18645373 | 0.74 | NUDT1 (0.68) | NUDT1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL22561760 | 0.73 | NUDT1 (0.41) | NUDT1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL19939690 | 0.70 | NUDT1 (0.45) | NUDT1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL22561758 | 0.70 | SCN9A (0.37) | ALDH1A1KDM4ESMN1; SMN2MAPK1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |