Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22562465 | 0.92 | TGFBR1 (0.44) | TGFBR1GRM5MEN1ALDH1A1CYP1A2 | |
| SCHEMBL22562212 | 0.91 | CYP11B1 (0.36) | TGFBR1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22562238 | 0.89 | MEN1 (0.34) | TGFBR1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22562237 | 0.87 | TGFBR1 (0.37) | TGFBR1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22562464 | 0.87 | TGFBR1 (0.44) | TGFBR1 | |
| SCHEMBL21278787 | 0.86 | MEN1 (0.42) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19942790 | 0.86 | CYP1A2 (0.37) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21278885 | 0.84 | MEN1 (0.40) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL19942772 | 0.84 | L3MBTL1 (0.41) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22563552 | 0.84 | MEN1 (0.42) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3418278-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |