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SCHEMBL22562379

SCHEMBL22562379

Cc1cc(C)c(-c2ccc3c4ccccc4n(-c4cc(-c5cccc(-c6ccccc6)n5)cc(-n5c6ccccc6c6ccc(-c7c(C)cc(C)cc7C)cc65)c4C(F)(F)F)c3c2)c(C)c1

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ ENPP1 P22413 1/20 0.31
▸ NPY5R Q15761 1/20 0.31
▸ METAP2 P50579 1/20 0.31
▸ GSK3B P49841 2/20 0.30
▸ TP53 P04637 1/20 0.30
▸ DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22562383 0.97 MEN1 (0.33) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562380 0.95 NPY5R (0.35) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562382 0.92 MEN1 (0.34) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562356 0.89 PDK2 (0.36) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562301 0.89 MAPT (0.34) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562298 0.88 MEN1 (0.36) MAPTMEN1RAB9AKMT2AMETAP2
SCHEMBL22562369 0.88 ADORA3 (0.37) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562473 0.87 GSK3B (0.33) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562359 0.87 PDK2 (0.36) MAPTMEN1RAB9AKMT2AENPP1
SCHEMBL22562266 0.87 MEN1 (0.35) MAPTMEN1RAB9AKMT2ANPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3418278-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 — — EP disclosed