SCHEMBL22562383

Cc1cc(C)c(-c2ccc3c4ccc(-c5c(C)cc(C)cc5C)cc4n(-c4cc(-c5cccc(-c6ccccc6)n5)cc(-n5c6cc(-c7c(C)cc(C)cc7C)ccc6c6ccc(-c7c(C)cc(C)cc7C)cc65)c4C(F)(F)F)c3c2)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	1/20	0.33

▸	RAB9A	P51151	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	MAPT	P10636	6/20	0.33

▸	METAP2	P50579	1/20	0.32

▸	TP53	P04637	1/20	0.32

▸	GSK3B	P49841	2/20	0.32

▸	DHODH	Q02127	2/20	0.31

▸	ENPP1	P22413	1/20	0.31

▸	HSD11B1	P28845	1/20	0.31

▸	CYP11B2	P19099	1/20	0.31

▸	MAT2A	P31153	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22562379	0.97	MAPT (0.31)	MEN1RAB9AKMT2AMAPTMETAP2
SCHEMBL22562382	0.93	MEN1 (0.34)	MEN1RAB9AKMT2AMAPTTP53
SCHEMBL22562380	0.92	NPY5R (0.35)	MEN1RAB9AKMT2AMAPTTP53
SCHEMBL22562298	0.90	MEN1 (0.36)	MEN1RAB9AKMT2AMAPTMETAP2
SCHEMBL22562296	0.88	MEN1 (0.40)	MEN1RAB9AKMT2AMAPTTP53
SCHEMBL22562357	0.88	PDK2 (0.38)	MEN1RAB9AKMT2AMAPTMETAP2
SCHEMBL22562299	0.88	MAPT (0.36)	MEN1RAB9AKMT2AMAPTMETAP2
SCHEMBL22562367	0.87	ADORA3 (0.39)	MEN1RAB9AKMT2AMAPTTP53
SCHEMBL22562614	0.87	MEN1 (0.40)	MEN1RAB9AKMT2AMAPTTP53
SCHEMBL22562358	0.86	PDK2 (0.38)	MEN1RAB9AKMT2AMAPTMETAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3418278-B1	ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES	CYNORA GMBH (DE)	2020-10-21	—	—	EP	disclosed