Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785538 | 0.88 | TSHR (0.58) | TSHRHIF1AFAAHTRPV1TDP1 | |
| SCHEMBL16816629 | 0.88 | TSHR (0.73) | TSHRHIF1AFAAHTRPV1ALDH1A1 | |
| SCHEMBL9007934 | 0.88 | TSHR (0.52) | TSHRHIF1AFAAHTRPV1TDP1 | |
| SCHEMBL23531396 | 0.85 | TDP1 (0.48) | TSHRHIF1ATDP1ALDH1A1 | |
| SCHEMBL6998148 | 0.85 | TSHR (0.54) | TSHRHIF1AFAAHTRPV1TDP1 | |
| SCHEMBL22626934 | 0.82 | BHMT (0.51) | TSHRFAAHTDP1GMNNPOLB | |
| SCHEMBL5056599 | 0.82 | TSHR (0.50) | TSHRHIF1AFAAHTRPV1TDP1 | |
| SCHEMBL28348510 | 0.81 | ALOX5 (0.42) | TSHRHIF1AFAAHTRPV1TDP1 | |
| SCHEMBL17369100 | 0.80 | HIF1A (0.75) | TSHRHIF1AFAAHTRPV1TDP1 | |
| SCHEMBL1676895 | 0.80 | HIF1A (0.75) | TSHRHIF1AFAAHTRPV1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725801-A2 | AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS | Chemical & Biopharmaceutical Laboratories of Patras S.A. (GR) | 2020-10-21 | — | — | EP | disclosed |