SCHEMBL22563364

SCHEMBL22563364

N#Cc1cc(-c2nc(-c3ccccc3)cc(-c3ccccc3)n2)cc(F)c1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.52
CYP11B2 P19099 2/20 0.52
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 5/20 0.42
HPGD P15428 3/20 0.42
MAPT P10636 2/20 0.42
NTSR1 P30989 1/20 0.42
KDM4E B2RXH2 4/20 0.42
ADORA2A P29274 3/20 0.42
ADORA1 P30542 3/20 0.42
ABCG2 Q9UNQ0 2/20 0.42
RXFP1 Q9HBX9 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
MAPK1 P28482 1/20 0.41
CSNK2A1 P68400 1/20 0.41
LMNA P02545 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
SQOR Q9Y6N5 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16122007 0.92 CYP11B1 (0.49) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL19942765 0.91 CYP11B1 (0.48) CYP11B1CYP11B2ALDH1A1HPGDKDM4E
SCHEMBL16122008 0.88 MEN1 (0.49) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL16122285 0.86 ALDH1A1 (0.46) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL22563534 0.83 L3MBTL1 (0.51) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL17545801 0.82 ABCG2 (0.46) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL16122013 0.82 ABCG2 (0.46) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL24324019 0.82 CYP11B1 (0.56) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL16122011 0.81 CYP11B1 (0.54) CYP11B1CYP11B2MEN1KMT2AALDH1A1
SCHEMBL20843302 0.80 ABCG2 (0.54) CYP11B1CYP11B2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed
EP-3580300-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OR51E2, OCIAD2 CYP11B1 1451/4885CYP11B2 770/4885MEN1 2472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.