Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19794380 | 0.92 | KDM4E (0.42) | KDM4EPARP1PDGFRBPDGFRACA12 | |
| SCHEMBL19933707 | 0.85 | ALDH1A1 (0.40) | KDM4EPARP1PDGFRBPDGFRACA12 | |
| SCHEMBL19933641 | 0.83 | KDM4E (0.39) | KDM4EPARP1PDGFRBPDGFRACA12 | |
| SCHEMBL18015696 | 0.81 | KDM4E (0.43) | KDM4EPARP1MAPTALDH1A1NPC1 | |
| SCHEMBL17899314 | 0.79 | CA12 (0.50) | KDM4EPARP1PDGFRBPDGFRACA12 | |
| SCHEMBL19933628 | 0.79 | ALDH1A1 (0.40) | KDM4EPARP1PDGFRBPDGFRACA12 | |
| SCHEMBL18015699 | 0.79 | KDM4E (0.39) | KDM4EPARP1PDGFRBPDGFRAMAPT | |
| SCHEMBL12786342 | 0.77 | KDM4E (0.54) | KDM4EPARP1PDGFRBPDGFRACA12 | |
| SCHEMBL22059854 | 0.77 | ALDH1A1 (0.41) | KDM4EMAPTL3MBTL1ALDH1A1CCR1 | |
| SCHEMBL30547066 | 0.76 | KDM4E (0.62) | KDM4EPARP1PDGFRBPDGFRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507294-B1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | disclosed |
| EP-3515925-B1 | BINUCLEAR METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |